A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals

نویسندگان

  • Hisashi Moriguchi
  • Yue Zhang
  • Makoto Mihara
  • Chifumi Sato
چکیده

Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).

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ADDENDUM: A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals

Editorial Note: A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals Scientific Reports has become aware of irregularities related to authors affiliations and the statement describing IRB approval in this paper. The situation is being investigated.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2012